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RNA-sequencing in non-small cell lung cancer shows gene downregulation of therapeutic targets in tumor tissue compared to non-malignant lung tissue

BACKGROUND: Gene expression of specific therapeutic targets in non-malignant lung tissue might play an important role in optimizing targeted therapies. This study aims to identify different expression patterns of fifteen genes important for targeted therapy in non-small cell lung cancer (NSCLC). MET...

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Detalles Bibliográficos
Autores principales: Reynders, Kobe, Wauters, Els, Moisse, Matthieu, Decaluwé, Herbert, De Leyn, Paul, Peeters, Stéphanie, Lambrecht, Maarten, Nackaerts, Kristiaan, Dooms, Christophe, Janssens, Wim, Vansteenkiste, Johan, Lambrechts, Diether, De Ruysscher, Dirk
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050654/
https://www.ncbi.nlm.nih.gov/pubmed/30016964
http://dx.doi.org/10.1186/s13014-018-1075-1