Ube2v1-mediated ubiquitination and degradation of Sirt1 promotes metastasis of colorectal cancer by epigenetically suppressing autophagy

BACKGROUND: Ubiquitination is a basic post-translational modification for cellular homeostasis, and members of the conjugating enzyme (E2) family are the key components of the ubiquitin–proteasome system. However, the role of E2 family in colorectal cancer (CRC) is largely unknown. Our study aimed t...

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Detalles Bibliográficos
Autores principales: Shen, Tong, Cai, Ling-Dong, Liu, Yu-Hong, Li, Shi, Gan, Wen-Juan, Li, Xiu-Ming, Wang, Jing-Ru, Guo, Peng-Da, Zhou, Qun, Lu, Xing-Xing, Sun, Li-Na, Li, Jian-Ming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050692/
https://www.ncbi.nlm.nih.gov/pubmed/30016968
http://dx.doi.org/10.1186/s13045-018-0638-9

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050692/
https://www.ncbi.nlm.nih.gov/pubmed/30016968
http://dx.doi.org/10.1186/s13045-018-0638-9

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