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Myocyte-specific overexpressing HDAC4 promotes myocardial ischemia/reperfusion injury

BACKGROUND: Histone deacetylases (HDACs) play a critical role in modulating myocardial protection and cardiomyocyte survivals. However, Specific HDAC isoforms in mediating myocardial ischemia/reperfusion injury remain currently unknown. We used cardiomyocyte-specific overexpression of active HDAC4 t...

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Detalles Bibliográficos
Autores principales: Zhang, Ling, Wang, Hao, Zhao, Yu, Wang, Jianguo, Dubielecka, Patrycja M., Zhuang, Shougang, Qin, Gangjian, Chin, Y Eugene, Kao, Race L., Zhao, Ting C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050730/
https://www.ncbi.nlm.nih.gov/pubmed/30134825
http://dx.doi.org/10.1186/s10020-018-0037-2