CDK4/6 inhibition in breast cancer: current practice and future directions

The cyclin D/cyclin-dependent kinases 4 and 6 (CDK4/6)–retinoblastoma protein (RB) pathway plays a key role in the proliferation of both normal breast epithelium and breast cancer cells. A strong rationale for inhibiting CDK4/6 in breast cancers has been present for many years. However, potent and s...

Descripción completa

Detalles Bibliográficos
Autores principales: Pernas, Sonia, Tolaney, Sara M., Winer, Eric P., Goel, Shom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2018
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050811/
https://www.ncbi.nlm.nih.gov/pubmed/30038670
http://dx.doi.org/10.1177/1758835918786451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050811/
https://www.ncbi.nlm.nih.gov/pubmed/30038670
http://dx.doi.org/10.1177/1758835918786451

Ejemplares similares