Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation

Curli amyloid fibers are produced as part of the extracellular biofilm matrix and are composed primarily of the major structural subunit CsgA. The CsgE chaperone facilitates the secretion of CsgA through CsgG by forming a cap at the base of the nonameric CsgG outer membrane pore. We elucidated a ser...

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Detalles Bibliográficos
Autores principales: Klein, Roger D., Shu, Qin, Cusumano, Zachary T., Nagamatsu, Kanna, Gualberto, Nathaniel C., Lynch, Aaron J. L., Wu, Chao, Wang, Wenjie, Jain, Neha, Pinkner, Jerome S., Amarasinghe, Gaya K., Hultgren, Scott J., Frieden, Carl, Chapman, Matthew R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050966/
https://www.ncbi.nlm.nih.gov/pubmed/30018113
http://dx.doi.org/10.1128/mBio.01349-18

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050966/
https://www.ncbi.nlm.nih.gov/pubmed/30018113
http://dx.doi.org/10.1128/mBio.01349-18

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