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Structure-Function Analysis of the Curli Accessory Protein CsgE Defines Surfaces Essential for Coordinating Amyloid Fiber Formation
Curli amyloid fibers are produced as part of the extracellular biofilm matrix and are composed primarily of the major structural subunit CsgA. The CsgE chaperone facilitates the secretion of CsgA through CsgG by forming a cap at the base of the nonameric CsgG outer membrane pore. We elucidated a ser...
Autores principales: | Klein, Roger D., Shu, Qin, Cusumano, Zachary T., Nagamatsu, Kanna, Gualberto, Nathaniel C., Lynch, Aaron J. L., Wu, Chao, Wang, Wenjie, Jain, Neha, Pinkner, Jerome S., Amarasinghe, Gaya K., Hultgren, Scott J., Frieden, Carl, Chapman, Matthew R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
American Society for Microbiology
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050966/ https://www.ncbi.nlm.nih.gov/pubmed/30018113 http://dx.doi.org/10.1128/mBio.01349-18 |
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