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Solubility Enhancement of Domperidone by Solvent Change In situ Micronization Technique

BACKGROUND: Domperidone (DOM), a dopamine receptor antagonist, is used as antiemetic for the treatment of gastroparesis, vomiting, and nausea. The low water solubility of DOM leads to a low dissolution rate and variable bioavailability. The aim of this study was to enhance the solubility of DOM by t...

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Detalles Bibliográficos
Autores principales:	Enteshari, Saeede, Varshosaz, Jaleh
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Medknow Publications & Media Pvt Ltd 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6050975/ https://www.ncbi.nlm.nih.gov/pubmed/30069440 http://dx.doi.org/10.4103/abr.abr_219_17

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