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Guiding the Differentiation Direction of Pancreatic Islet-Derived Stem Cells by Glycated Collagen
The microenvironment is an important factor of stem cells regulating their maintenance, survival, and differentiation. The glycation of proteins with reducing sugars through nonenzymatic reactions induces the collagen cross-linking, which causes tissue stiffening, which is enhanced during aging and...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051021/ https://www.ncbi.nlm.nih.gov/pubmed/30057625 http://dx.doi.org/10.1155/2018/6143081 |