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The Isoquinoline Alkaloid Dauricine Targets Multiple Molecular Pathways to Ameliorate Alzheimer-Like Pathological Changes In Vitro

Alzheimer's disease (AD), the most common neurodegenerative disease, has no effective treatment. Dauricine (DAU), a benzyl tetrahydroisoquinoline alkaloid isolated from the root of Menispermum dauricum DC, reportedly has neuroprotective effects in cerebral ischemia. Here, we investigated the ef...

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Detalles Bibliográficos
Autores principales: Liu, Pan, Chen, Xiao, Zhou, Haizhe, Wang, Liqun, Zhang, Zaijun, Ren, Xiaohu, Zhu, Feiqi, Guo, Yi, Huang, Xinfeng, Liu, Jianjun, Spencer, Peter S., Yang, Xifei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051032/
https://www.ncbi.nlm.nih.gov/pubmed/30057671
http://dx.doi.org/10.1155/2018/2025914