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ATM Induces Cell Death with Autophagy in Response to H(2)O(2) Specifically in Caenorhabditis elegans Nondividing Cells

INTRODUCTION: Ataxia-telangiectasia-mutated (ATM) kinase is a master regulator of the DNA damage response and is directly activated by reactive oxygen species (ROSs) in addition to DNA double-stranded breaks. However, the physiological function of the response to ROSs is not understood. PURPOSE: In...

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Detalles Bibliográficos
Autores principales: Moriwaki, Takahito, Yamasaki, Akira, Zhang-Akiyama, Qiu-Mei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051064/
https://www.ncbi.nlm.nih.gov/pubmed/30057676
http://dx.doi.org/10.1155/2018/3862070