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ATM Induces Cell Death with Autophagy in Response to H(2)O(2) Specifically in Caenorhabditis elegans Nondividing Cells
INTRODUCTION: Ataxia-telangiectasia-mutated (ATM) kinase is a master regulator of the DNA damage response and is directly activated by reactive oxygen species (ROSs) in addition to DNA double-stranded breaks. However, the physiological function of the response to ROSs is not understood. PURPOSE: In...
Autores principales: | Moriwaki, Takahito, Yamasaki, Akira, Zhang-Akiyama, Qiu-Mei |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051064/ https://www.ncbi.nlm.nih.gov/pubmed/30057676 http://dx.doi.org/10.1155/2018/3862070 |
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