Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke

INTRODUCTION: Stroke is one of the most common neurological disorders with high mortality rates. A large financial burden is imposed on the families and health systems of countries in addition to the problems related to the disabilities caused by the disease for the patients. Extensive research is b...

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Autores principales: Saadat, Payam, Ahmadi Ahangar, Alijan, Babaei, Mansor, Kalantar, Mandana, Bayani, Mohammad Ali, Barzegar, Hiva, Gholinia, Hemmat, Zahedi Tajrishi, Farbod, Faraji, Sekineh, Frajzadeh, Fatemeh
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
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Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051071/
https://www.ncbi.nlm.nih.gov/pubmed/30057737
http://dx.doi.org/10.1155/2018/6580178
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author Saadat, Payam
Ahmadi Ahangar, Alijan
Babaei, Mansor
Kalantar, Mandana
Bayani, Mohammad Ali
Barzegar, Hiva
Gholinia, Hemmat
Zahedi Tajrishi, Farbod
Faraji, Sekineh
Frajzadeh, Fatemeh
author_facet Saadat, Payam
Ahmadi Ahangar, Alijan
Babaei, Mansor
Kalantar, Mandana
Bayani, Mohammad Ali
Barzegar, Hiva
Gholinia, Hemmat
Zahedi Tajrishi, Farbod
Faraji, Sekineh
Frajzadeh, Fatemeh
author_sort Saadat, Payam
collection PubMed
description INTRODUCTION: Stroke is one of the most common neurological disorders with high mortality rates. A large financial burden is imposed on the families and health systems of countries in addition to the problems related to the disabilities caused by the disease for the patients. Extensive research is being conducted on the disease, including studies seeking possible relationships between some biomarkers such as uric acid and stroke. METHODS: This descriptive-analytic cross-sectional study was conducted on 170 stroke patients at Babol Ayatollah Rohani Hospital during 2015-2016. Serum uric acid (SUA) levels were measured and recorded at admission time. Patients' demographic data as well as the stroke type and some of their risk factors were entered in a checklist. The data were analyzed by SPSS.v.23 using chi-square and logistic regression tests. P < 0.05 was considered as significant in all analyses. RESULTS: Of the total 170 included patients, 57% had normal, 25% had low, and the remaining patients (18%) had high SUA levels. There was no significant difference in SUA levels in different types of stroke in both genders. Diabetic ischemic embolic patients had higher levels of SUA than diabetic ischemic thrombotic cases. Patients with low magnesium levels had higher rate of low levels of SUA in ischemic stroke. CONCLUSION: Serum uric acid levels are not associated with stroke types and gender. Diabetic embolic ischemic stroke cases had high SUA levels than thrombotic types and in ischemic stroke patients with low serum levels of magnesium, SUA levels were also lower.
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spelling pubmed-60510712018-07-29 Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke Saadat, Payam Ahmadi Ahangar, Alijan Babaei, Mansor Kalantar, Mandana Bayani, Mohammad Ali Barzegar, Hiva Gholinia, Hemmat Zahedi Tajrishi, Farbod Faraji, Sekineh Frajzadeh, Fatemeh Stroke Res Treat Research Article INTRODUCTION: Stroke is one of the most common neurological disorders with high mortality rates. A large financial burden is imposed on the families and health systems of countries in addition to the problems related to the disabilities caused by the disease for the patients. Extensive research is being conducted on the disease, including studies seeking possible relationships between some biomarkers such as uric acid and stroke. METHODS: This descriptive-analytic cross-sectional study was conducted on 170 stroke patients at Babol Ayatollah Rohani Hospital during 2015-2016. Serum uric acid (SUA) levels were measured and recorded at admission time. Patients' demographic data as well as the stroke type and some of their risk factors were entered in a checklist. The data were analyzed by SPSS.v.23 using chi-square and logistic regression tests. P < 0.05 was considered as significant in all analyses. RESULTS: Of the total 170 included patients, 57% had normal, 25% had low, and the remaining patients (18%) had high SUA levels. There was no significant difference in SUA levels in different types of stroke in both genders. Diabetic ischemic embolic patients had higher levels of SUA than diabetic ischemic thrombotic cases. Patients with low magnesium levels had higher rate of low levels of SUA in ischemic stroke. CONCLUSION: Serum uric acid levels are not associated with stroke types and gender. Diabetic embolic ischemic stroke cases had high SUA levels than thrombotic types and in ischemic stroke patients with low serum levels of magnesium, SUA levels were also lower. Hindawi 2018-07-02 /pmc/articles/PMC6051071/ /pubmed/30057737 http://dx.doi.org/10.1155/2018/6580178 Text en Copyright © 2018 Payam Saadat et al. https://creativecommons.org/licenses/by/4.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Saadat, Payam
Ahmadi Ahangar, Alijan
Babaei, Mansor
Kalantar, Mandana
Bayani, Mohammad Ali
Barzegar, Hiva
Gholinia, Hemmat
Zahedi Tajrishi, Farbod
Faraji, Sekineh
Frajzadeh, Fatemeh
Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke
title Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke
title_full Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke
title_fullStr Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke
title_full_unstemmed Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke
title_short Relationship of Serum Uric Acid Level with Demographic Features, Risk Factors, Severity, Prognosis, Serum Levels of Vitamin D, Calcium, and Magnesium in Stroke
title_sort relationship of serum uric acid level with demographic features, risk factors, severity, prognosis, serum levels of vitamin d, calcium, and magnesium in stroke
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051071/
https://www.ncbi.nlm.nih.gov/pubmed/30057737
http://dx.doi.org/10.1155/2018/6580178
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