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Emodin, Physcion, and Crude Extract of Rhamnus sphaerosperma var. pubescens Induce Mixed Cell Death, Increase in Oxidative Stress, DNA Damage, and Inhibition of AKT in Cervical and Oral Squamous Carcinoma Cell Lines

There have been few studies on the pharmacological properties of Rhamnus sphaerosperma var. pubescens, a native Brazilian species popularly known as “fruto-de-pombo.” The aim of this study was to investigate the scavenging capacity of emodin, physcion, and the ethanolic crude extract of Rhamnus spha...

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Detalles Bibliográficos
Autores principales: Moreira, Thais Fernanda, Sorbo, Juliana Maria, Souza, Felipe de Oliveira, Fernandes, Barbara Colatto, Ocampos, Fernanda Maria Marins, de Oliveira, Daniella Maria Soares, Arcaro, Carlos Alberto, Assis, Renata Pires, Barison, Andersson, Miguel, Obdulio Gomes, Baviera, Amanda Martins, Soares, Christiane Pienna, Brunetti, Iguatemy Lourenço
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051077/
https://www.ncbi.nlm.nih.gov/pubmed/30057674
http://dx.doi.org/10.1155/2018/2390234