CTLA4Ig Improves Murine iTreg Induction via TGFβ and Suppressor Function In Vitro

Blockade of the CD28:CD80/86 costimulatory pathway has been shown to be potent in blocking T cell activation in vitro and in vivo. The costimulation blocker CTLA4Ig has been approved for the treatment of autoimmune diseases and transplant rejection. The therapeutic application of regulatory T cells...

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Detalles Bibliográficos
Autores principales: Pilat, Nina, Mahr, Benedikt, Gattringer, Martina, Baranyi, Ulrike, Wekerle, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051081/
https://www.ncbi.nlm.nih.gov/pubmed/30057914
http://dx.doi.org/10.1155/2018/2484825

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051081/
https://www.ncbi.nlm.nih.gov/pubmed/30057914
http://dx.doi.org/10.1155/2018/2484825

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