FM19G11 inhibits O(6)‐methylguanine DNA‐methyltransferase expression under both hypoxic and normoxic conditions

FM19G11 is a small molecular agent that inhibits hypoxia‐inducible factor‐1‐alpha (HIF‐1α) and other signaling pathways. In this study, we characterized the modulating effects of FM19G11 on O(6)‐methylguanine DNA‐methyltransferase (MGMT), the main regulator of temozolomide (TMZ) resistance in gliobl...

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Detalles Bibliográficos
Autores principales: You, Chao‐guo, Sheng, Han‐song, Xie, Chao‐ran, Zhang, Nu, Zheng, Xue‐sheng
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Cancer Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051152/
https://www.ncbi.nlm.nih.gov/pubmed/29761922
http://dx.doi.org/10.1002/cam4.1551

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051152/
https://www.ncbi.nlm.nih.gov/pubmed/29761922
http://dx.doi.org/10.1002/cam4.1551

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