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Chronic myelogenous leukemia on target

Chronic myelogenous leukemia (CML) is commonly treated with tyrosine kinase inhibitors (TKIs) that inhibit the pro‐leukemic activity of the BCR‐ABL1 oncoprotein. Despite the therapeutic progress mediated by TKI use, off‐target effects, treatment‐induced drug resistance, and the limited effect of the...

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Detalles Bibliográficos
Autores principales: Némethová, Veronika, Rázga, Filip
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051163/
https://www.ncbi.nlm.nih.gov/pubmed/29905026
http://dx.doi.org/10.1002/cam4.1604