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Reversal learning paradigm reveals deficits in cognitive flexibility in the Fmr1 knockout male mouse

Background: Loss of FMR1 is associated with Fragile X syndrome, amongst the most prevalent inherited intellectual disability. Despite extensive research in this area, previous studies have failed to detect consistent evidence of cognitive impairments in the Morris water maze (MWM) task in the Fmr1 k...

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Detalles Bibliográficos
Autores principales: Nolan, Suzanne O., Lugo, Joaquin N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: F1000 Research Limited 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051189/
https://www.ncbi.nlm.nih.gov/pubmed/30057755
http://dx.doi.org/10.12688/f1000research.14969.1