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Reversal learning paradigm reveals deficits in cognitive flexibility in the Fmr1 knockout male mouse
Background: Loss of FMR1 is associated with Fragile X syndrome, amongst the most prevalent inherited intellectual disability. Despite extensive research in this area, previous studies have failed to detect consistent evidence of cognitive impairments in the Morris water maze (MWM) task in the Fmr1 k...
Autores principales: | , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
F1000 Research Limited
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051189/ https://www.ncbi.nlm.nih.gov/pubmed/30057755 http://dx.doi.org/10.12688/f1000research.14969.1 |