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A Highly Efficient Synthesis of Polyubiquitin Chains

A robust, microwave‐assisted, highly efficient, solid‐phase peptide synthesis method for preparing isopeptide‐linked 62‐mer and 76‐mer isoubiquitins and polyubiquitin is developed. The strategy avoids the use of costly resins and pseudoprolines, and the isopeptide‐linked building blocks can be assem...

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Detalles Bibliográficos
Autores principales: Qu, Qian, Pan, Man, Gao, Shuai, Zheng, Qing‐Yun, Yu, Yuan‐Yuan, Su, Jia‐Can, Li, Xiang, Hu, Hong‐Gang
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051384/
https://www.ncbi.nlm.nih.gov/pubmed/30027052
http://dx.doi.org/10.1002/advs.201800234