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The GTPase Rab43 Controls the Anterograde ER-Golgi Trafficking and Sorting of GPCRs

G-protein-coupled receptors (GPCRs) constitute the largest superfamily of cell-surface signaling proteins. However, mechanisms underlying their surface targeting and sorting are poorly understood. Here, we screen the Rab family of small GTPases in the surface transport of multiple GPCRs. We find tha...

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Detalles Bibliográficos
Autores principales: Li, Chunman, Wei, Zhe, Fan, Yi, Huang, Wei, Su, Yunchao, Li, Honglin, Dong, Zheng, Fukuda, Mitsunori, Khater, Mostafa, Wu, Guangyu
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051424/
https://www.ncbi.nlm.nih.gov/pubmed/29069590
http://dx.doi.org/10.1016/j.celrep.2017.10.011