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p38α blocks brown adipose tissue thermogenesis through p38δ inhibition

Adipose tissue has emerged as an important regulator of whole-body metabolism, and its capacity to dissipate energy in the form of heat has acquired a special relevance in recent years as potential treatment for obesity. In this context, the p38MAPK pathway has arisen as a key player in the thermoge...

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Detalles Bibliográficos
Autores principales: Matesanz, Nuria, Nikolic, Ivana, Leiva, Magdalena, Pulgarín-Alfaro, Marta, Santamans, Ayelén M., Bernardo, Edgar, Mora, Alfonso, Herrera-Melle, Leticia, Rodríguez, Elena, Beiroa, Daniel, Caballero, Ainoa, Martín-García, Elena, Acín-Pérez, Rebeca, Hernández-Cosido, Lourdes, Leiva-Vega, Luis, Torres, Jorge L., Centeno, Francisco, Nebreda, Angel R., Enríquez, José Antonio, Nogueiras, Rubén, Marcos, Miguel, Sabio, Guadalupe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051667/
https://www.ncbi.nlm.nih.gov/pubmed/29979672
http://dx.doi.org/10.1371/journal.pbio.2004455