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p38α blocks brown adipose tissue thermogenesis through p38δ inhibition
Adipose tissue has emerged as an important regulator of whole-body metabolism, and its capacity to dissipate energy in the form of heat has acquired a special relevance in recent years as potential treatment for obesity. In this context, the p38MAPK pathway has arisen as a key player in the thermoge...
Autores principales: | Matesanz, Nuria, Nikolic, Ivana, Leiva, Magdalena, Pulgarín-Alfaro, Marta, Santamans, Ayelén M., Bernardo, Edgar, Mora, Alfonso, Herrera-Melle, Leticia, Rodríguez, Elena, Beiroa, Daniel, Caballero, Ainoa, Martín-García, Elena, Acín-Pérez, Rebeca, Hernández-Cosido, Lourdes, Leiva-Vega, Luis, Torres, Jorge L., Centeno, Francisco, Nebreda, Angel R., Enríquez, José Antonio, Nogueiras, Rubén, Marcos, Miguel, Sabio, Guadalupe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051667/ https://www.ncbi.nlm.nih.gov/pubmed/29979672 http://dx.doi.org/10.1371/journal.pbio.2004455 |
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