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A genome-wide screen of Epstein-Barr virus proteins that modulate host SUMOylation identifies a SUMO E3 ligase conserved in herpesviruses

Many cellular processes pertinent for viral infection are regulated by the addition of small ubiquitin-like modifiers (SUMO) to key regulatory proteins, making SUMOylation an important mechanism by which viruses can commandeer cellular pathways. Epstein-Barr virus (EBV) is a master at manipulating o...

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Detalles Bibliográficos
Autores principales: De La Cruz-Herrera, Carlos F., Shire, Kathy, Siddiqi, Umama Z., Frappier, Lori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051671/
https://www.ncbi.nlm.nih.gov/pubmed/29979787
http://dx.doi.org/10.1371/journal.ppat.1007176