Aspartate is an endogenous metabolic limitation for tumour growth

Defining the metabolic limitations of tumour growth will help develop cancer therapies(1). Cancer cells proliferate slower in tumours than in standard culture conditions, indicating that a metabolic limitation may restrict cell proliferation in vivo. Aspartate synthesis can limit cancer cell prolife...

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Detalles Bibliográficos
Autores principales: Sullivan, Lucas B., Luengo, Alba, Danai, Laura V., Bush, Lauren N., Diehl, Frances F., Hosios, Aaron M., Lau, Allison N., Elmiligy, Sarah, Malstrom, Scott, Lewis, Caroline A., Vander Heiden, Matthew G.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051729/
https://www.ncbi.nlm.nih.gov/pubmed/29941931
http://dx.doi.org/10.1038/s41556-018-0125-0

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051729/
https://www.ncbi.nlm.nih.gov/pubmed/29941931
http://dx.doi.org/10.1038/s41556-018-0125-0

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