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Nuclear F-actin and myosins drive relocalization of heterochromatic breaks

Heterochromatin mostly comprises repeated DNA sequences prone to ectopic recombination. In Drosophila cells, ‘safe’ homologous recombination repair of heterochromatic double-strand breaks relies on the relocalization of repair sites to the nuclear periphery before strand invasion. Mechanisms respons...

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Detalles Bibliográficos
Autores principales: Caridi, Christopher P., D’Agostino, Carla, Ryu, Taehyun, Zapotoczny, Grzegorz, Delabaere, Laetitia, Li, Xiao, Khodaverdian, Varandt Y., Amaral, Nuno, Lin, Emily, Rau, Alesandra, Chiolo, Irene
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051730/
https://www.ncbi.nlm.nih.gov/pubmed/29925946
http://dx.doi.org/10.1038/s41586-018-0242-8