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Nuclear F-actin and myosins drive relocalization of heterochromatic breaks
Heterochromatin mostly comprises repeated DNA sequences prone to ectopic recombination. In Drosophila cells, ‘safe’ homologous recombination repair of heterochromatic double-strand breaks relies on the relocalization of repair sites to the nuclear periphery before strand invasion. Mechanisms respons...
Autores principales: | Caridi, Christopher P., D’Agostino, Carla, Ryu, Taehyun, Zapotoczny, Grzegorz, Delabaere, Laetitia, Li, Xiao, Khodaverdian, Varandt Y., Amaral, Nuno, Lin, Emily, Rau, Alesandra, Chiolo, Irene |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051730/ https://www.ncbi.nlm.nih.gov/pubmed/29925946 http://dx.doi.org/10.1038/s41586-018-0242-8 |
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