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TRPV4 is the temperature-sensitive ion channel of human sperm

Ion channels control the ability of human sperm to fertilize the egg by triggering hyperactivated motility, which is regulated by membrane potential, intracellular pH, and cytosolic calcium. Previous studies unraveled three essential ion channels that regulate these parameters: (1) the Ca(2+) channe...

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Detalles Bibliográficos
Autores principales: Mundt, Nadine, Spehr, Marc, Lishko, Polina V
Formato: Online Artículo Texto
Lenguaje:English
Publicado: eLife Sciences Publications, Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051745/
https://www.ncbi.nlm.nih.gov/pubmed/29963982
http://dx.doi.org/10.7554/eLife.35853