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Progressive brain rich-club network disruption from clinically isolated syndrome towards multiple sclerosis

OBJECTIVE: To investigate the rich-club organization in clinically isolated syndrome (CIS) and multiple sclerosis (MS), and to characterize its relationships with physical disabilities and cognitive impairments. METHODS: We constructed high-resolution white matter (WM) structural networks in 41 CIS,...

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Detalles Bibliográficos
Autores principales: Shu, Ni, Duan, Yunyun, Huang, Jing, Ren, Zhuoqiong, Liu, Zheng, Dong, Huiqing, Barkhof, Frederik, Li, Kuncheng, Liu, Yaou
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6051763/
https://www.ncbi.nlm.nih.gov/pubmed/30035017
http://dx.doi.org/10.1016/j.nicl.2018.03.034