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Inactivation of TCA cycle enhances Staphylococcus aureus persister cell formation in stationary phase

Persister cells constitute a small subpopulation of bacteria that display remarkably high antibiotic tolerance and for pathogens such as Staphylococcus aureus are suspected as culprits of chronic and recurrent infections. Persisters formed during exponential growth are characterized by low ATP level...

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Detalles Bibliográficos
Autores principales: Wang, Ying, Bojer, Martin Saxtorph, George, Shilpa Elizabeth, Wang, Zhihao, Jensen, Peter Ruhdal, Wolz, Christiane, Ingmer, Hanne
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052003/
https://www.ncbi.nlm.nih.gov/pubmed/30022089
http://dx.doi.org/10.1038/s41598-018-29123-0