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Non-canonicaly recruited TCRαβCD8αα IELs recognize microbial antigens

In the gut, various subsets of intraepithelial T cells (IELs) respond to self or non-self-antigens derived from the body, diet, commensal and pathogenic microbiota. Dominant subset of IELs in the small intestine are TCRαβCD8αα(+) cells, which are derived from immature thymocytes that express self-re...

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Detalles Bibliográficos
Autores principales: Wojciech, Lukasz, Szurek, Edyta, Kuczma, Michal, Cebula, Anna, Elhefnawy, Wessam R., Pietrzak, Maciej, Rempala, Grzegorz, Ignatowicz, Leszek
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052027/
https://www.ncbi.nlm.nih.gov/pubmed/30022086
http://dx.doi.org/10.1038/s41598-018-29073-7