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Non-canonicaly recruited TCRαβCD8αα IELs recognize microbial antigens
In the gut, various subsets of intraepithelial T cells (IELs) respond to self or non-self-antigens derived from the body, diet, commensal and pathogenic microbiota. Dominant subset of IELs in the small intestine are TCRαβCD8αα(+) cells, which are derived from immature thymocytes that express self-re...
Autores principales: | Wojciech, Lukasz, Szurek, Edyta, Kuczma, Michal, Cebula, Anna, Elhefnawy, Wessam R., Pietrzak, Maciej, Rempala, Grzegorz, Ignatowicz, Leszek |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052027/ https://www.ncbi.nlm.nih.gov/pubmed/30022086 http://dx.doi.org/10.1038/s41598-018-29073-7 |
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