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Electrostatic Tuning of the Ligand Binding Mechanism by Glu27 in Nitrophorin 7

Nitrophorins (NP) 1–7 are NO-carrying heme proteins found in the saliva of the blood-sucking insect Rhodnius prolixus. The isoform NP7 displays peculiar properties, such as an abnormally high isoelectric point, the ability to bind negatively charged membranes, and a strong pH sensitivity of NO affin...

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Detalles Bibliográficos
Autores principales: Abbruzzetti, Stefania, Allegri, Alessandro, Bidon-Chanal, Axel, Ogata, Hideaki, Soavi, Giancarlo, Cerullo, Giulio, Bruno, Stefano, Montali, Chiara, Luque, F. Javier, Viappiani, Cristiano
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052033/
https://www.ncbi.nlm.nih.gov/pubmed/30022039
http://dx.doi.org/10.1038/s41598-018-29182-3