Frontotemporal Dementia-Associated N279K Tau Mutation Localizes at the Nuclear Compartment

Tau is a microtubule-associated protein that plays an important role in Alzheimer’s disease and related tauopathies. Approximately one-half of all cases of Frontotemporal dementia with parkinsonism-17 (FTDP-17) are caused by mutations in the MAPT gene. The N279K mutation is one of the three mutation...

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Detalles Bibliográficos
Autores principales: Ritter, Maxi L., Avila, Jesús, García-Escudero, Vega, Hernández, Félix, Pérez, Mar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Neuroscience
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052045/
https://www.ncbi.nlm.nih.gov/pubmed/30050413
http://dx.doi.org/10.3389/fncel.2018.00202

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052045/
https://www.ncbi.nlm.nih.gov/pubmed/30050413
http://dx.doi.org/10.3389/fncel.2018.00202

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