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The Current State and Future of CRISPR-Cas9 gRNA Design Tools
Recent years have seen the development of computational tools to assist researchers in performing CRISPR-Cas9 experiment optimally. More specifically, these tools aim to maximize on-target activity (guide efficiency) while also minimizing potential off-target effects (guide specificity) by analyzing...
| Autores principales: | , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052051/ https://www.ncbi.nlm.nih.gov/pubmed/30050439 http://dx.doi.org/10.3389/fphar.2018.00749 |