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The Current State and Future of CRISPR-Cas9 gRNA Design Tools

Recent years have seen the development of computational tools to assist researchers in performing CRISPR-Cas9 experiment optimally. More specifically, these tools aim to maximize on-target activity (guide efficiency) while also minimizing potential off-target effects (guide specificity) by analyzing...

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Detalles Bibliográficos
Autores principales:	Wilson, Laurence O. W., O’Brien, Aidan R., Bauer, Denis C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052051/ https://www.ncbi.nlm.nih.gov/pubmed/30050439 http://dx.doi.org/10.3389/fphar.2018.00749

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