Triptolide attenuates proteinuria and podocyte apoptosis via inhibition of NF-κB/GADD45B

Podocyte injury is a primary contributor to proteinuria. Triptolide is a major active component of Tripterygium wilfordii Hook F that exhibits potent antiproteinuric effects. We used our previously developed in vivo zebrafish model of inducible podocyte-target injury and found that triptolide treatm...

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Detalles Bibliográficos
Autores principales: Wang, Ling, Zhang, Liwen, Hou, Qing, Zhu, Xiaodong, Chen, Zhaohong, Liu, Zhihong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052061/
https://www.ncbi.nlm.nih.gov/pubmed/30022148
http://dx.doi.org/10.1038/s41598-018-29203-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052061/
https://www.ncbi.nlm.nih.gov/pubmed/30022148
http://dx.doi.org/10.1038/s41598-018-29203-1

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