Endocrine cell type sorting and mature architecture in the islets of Langerhans require expression of Roundabout receptors in β cells

Pancreatic islets of Langerhans display characteristic spatial architecture of their endocrine cell types. This architecture is critical for cell-cell communication and coordinated hormone secretion. Islet architecture is disrupted in type-2 diabetes. Moreover, the generation of architecturally corr...

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Detalles Bibliográficos
Autores principales: Adams, Melissa T., Gilbert, Jennifer M., Hinojosa Paiz, Jesus, Bowman, Faith M., Blum, Barak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052079/
https://www.ncbi.nlm.nih.gov/pubmed/30022126
http://dx.doi.org/10.1038/s41598-018-29118-x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052079/
https://www.ncbi.nlm.nih.gov/pubmed/30022126
http://dx.doi.org/10.1038/s41598-018-29118-x

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