Potent effect of the MDM2 inhibitor AMG232 on suppression of glioblastoma stem cells

Testing new ways to identify untapped opportunities for glioblastoma therapies remains highly significant. Amplification and overexpression of MDM2 gene is frequent in glioblastoma and disrupting the MDM2−p53 interaction is a promising strategy to treat the cancer. RG7112 is the first-in class inhib...

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Detalles Bibliográficos
Autores principales: Her, Nam-Gu, Oh, Jeong-Woo, Oh, Yun Jeong, Han, Suji, Cho, Hee Jin, Lee, Yeri, Ryu, Gyu Ha, Nam, Do-Hyun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052082/
https://www.ncbi.nlm.nih.gov/pubmed/30022047
http://dx.doi.org/10.1038/s41419-018-0825-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052082/
https://www.ncbi.nlm.nih.gov/pubmed/30022047
http://dx.doi.org/10.1038/s41419-018-0825-1

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