Identification of Novel Mycobacterial Inhibitors Against Mycobacterial Protein Kinase G

Protein kinase G (PknG) is a eukaryotic-like serine/threonine kinase that is expressed by Mycobacterium tuberculosis and promotes survival of mycobacteria in host macrophages by suppressing phagosome-lysosome fusion. Thus, compounds showing inhibitory activity against PknG are promising anti-mycobac...

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Detalles Bibliográficos
Autores principales: Kanehiro, Yuichi, Tomioka, Haruaki, Pieters, Jean, Tatano, Yutaka, Kim, Hyoji, Iizasa, Hisashi, Yoshiyama, Hironori
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Microbiology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052090/
https://www.ncbi.nlm.nih.gov/pubmed/30050511
http://dx.doi.org/10.3389/fmicb.2018.01517

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052090/
https://www.ncbi.nlm.nih.gov/pubmed/30050511
http://dx.doi.org/10.3389/fmicb.2018.01517

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