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Crosstalk between hepatic tumor cells and macrophages via Wnt/β-catenin signaling promotes M2-like macrophage polarization and reinforces tumor malignant behaviors

Tumor-associated macrophages (TAMs) are a major component of tumor microenvironment (TME) and play pivotal roles in the progression of hepatocellular carcinoma (HCC). Wnt signaling is evolutionarily conserved and participates in liver tumorigenesis. Several studies have shown that macrophage-derived...

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Detalles Bibliográficos
Autores principales: Yang, Yang, Ye, Yu-Chen, Chen, Yan, Zhao, Jun-Long, Gao, Chun-Chen, Han, Hua, Liu, Wen-Chao, Qin, Hong-Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052107/
https://www.ncbi.nlm.nih.gov/pubmed/30022048
http://dx.doi.org/10.1038/s41419-018-0818-0