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TBK-binding protein 1 regulates IL-15-induced autophagy and NKT cell survival

The cytokine IL-15 mediates development and survival of immune cells, including natural killer T (NKT) cells, but the underlying mechanism of IL-15 function is incompletely understood. Here we show that IL-15 induces autophagy in NKT cells with a mechanism that involves a crucial signaling component...

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Detalles Bibliográficos
Autores principales: Zhu, Lele, Xie, Xiaoping, Zhang, Lingyun, Wang, Hui, Jie, Zuliang, Zhou, Xiaofei, Shi, Jianhong, Zhao, Shuli, Zhang, Boxiang, Cheng, Xuhong, Sun, Shao-Cong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052109/
https://www.ncbi.nlm.nih.gov/pubmed/30022064
http://dx.doi.org/10.1038/s41467-018-05097-5