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Genetic Adaptation of a Mevalonate Pathway Deficient Mutant in Staphylococcus aureus

In this study we addressed the question how a mevalonate (MVA)-auxotrophic Staphylococcus aureusΔmvaS mutant can revert to prototrophy. This mutant couldn’t grow in the absence of MVA. However, after a long lag-phase of 4–6 days the mutant adapted from auxotrophic to prototrophic phenotype. During t...

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Detalles Bibliográficos
Autores principales: Reichert, Sebastian, Ebner, Patrick, Bonetti, Eve-Julie, Luqman, Arif, Nega, Mulugeta, Schrenzel, Jacques, Spröer, Cathrin, Bunk, Boyke, Overmann, Jörg, Sass, Peter, François, Patrice, Götz, Friedrich
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052127/
https://www.ncbi.nlm.nih.gov/pubmed/30050520
http://dx.doi.org/10.3389/fmicb.2018.01539