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Immature particles and capsid-free viral RNA produced by Yellow fever virus-infected cells stimulate plasmacytoid dendritic cells to secrete interferons

Plasmacytoid dendritic cells (pDCs) are specialized in the production of interferons (IFNs) in response to viral infections. The Flaviviridae family comprises enveloped RNA viruses such as Hepatitis C virus (HCV) and Dengue virus (DENV). Cell-free flaviviridae virions poorly stimulate pDCs to produc...

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Detalles Bibliográficos
Autores principales: Sinigaglia, Laura, Gracias, Ségolène, Décembre, Elodie, Fritz, Matthieu, Bruni, Daniela, Smith, Nikaïa, Herbeuval, Jean-Philippe, Martin, Annette, Dreux, Marlène, Tangy, Frédéric, Jouvenet, Nolwenn
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052170/
https://www.ncbi.nlm.nih.gov/pubmed/30022130
http://dx.doi.org/10.1038/s41598-018-29235-7