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Immature particles and capsid-free viral RNA produced by Yellow fever virus-infected cells stimulate plasmacytoid dendritic cells to secrete interferons
Plasmacytoid dendritic cells (pDCs) are specialized in the production of interferons (IFNs) in response to viral infections. The Flaviviridae family comprises enveloped RNA viruses such as Hepatitis C virus (HCV) and Dengue virus (DENV). Cell-free flaviviridae virions poorly stimulate pDCs to produc...
Autores principales: | Sinigaglia, Laura, Gracias, Ségolène, Décembre, Elodie, Fritz, Matthieu, Bruni, Daniela, Smith, Nikaïa, Herbeuval, Jean-Philippe, Martin, Annette, Dreux, Marlène, Tangy, Frédéric, Jouvenet, Nolwenn |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052170/ https://www.ncbi.nlm.nih.gov/pubmed/30022130 http://dx.doi.org/10.1038/s41598-018-29235-7 |
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