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Rifampin- or Capreomycin-Induced Remodeling of the Mycobacterium smegmatis Mycolic Acid Layer Is Mitigated in Synergistic Combinations with Cationic Antimicrobial Peptides

The mycobacterial cell wall affords natural resistance to antibiotics. Antimicrobial peptides (AMPs) modify the surface properties of mycobacteria and can act synergistically with antibiotics from differing classes. Here, we investigate the response of Mycobacterium smegmatis to the presence of rifa...

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Detalles Bibliográficos
Autores principales: Man, DeDe Kwun-Wai, Kanno, Tokuwa, Manzo, Giorgia, Robertson, Brian D., Lam, Jenny K. W., Mason, A. James
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052339/
https://www.ncbi.nlm.nih.gov/pubmed/30021876
http://dx.doi.org/10.1128/mSphere.00218-18