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Loss of sirtuin 1 and mitofusin 2 contributes to enhanced ischemia/reperfusion injury in aged livers

Ischemia/reperfusion (I/R) injury is a causative factor contributing to morbidity and mortality during liver resection and transplantation. Livers from elderly patients have a poorer recovery from these surgeries, indicating reduced reparative capacity with aging. Mechanisms underlying this age‐medi...

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Detalles Bibliográficos
Autores principales: Chun, Sung Kook, Lee, Sooyeon, Flores‐Toro, Joseph, U, Rebecca Y., Yang, Ming‐Jim, Go, Kristina L., Biel, Thomas G., Miney, Catherine E., Pierre Louis, Schiley, Law, Brian K., Law, Mary E., Thomas, Elizabeth M., Behrns, Kevin E., Leeuwenburgh, Christiaan, Kim, Jae‐Sung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052398/
https://www.ncbi.nlm.nih.gov/pubmed/29774638
http://dx.doi.org/10.1111/acel.12761