Defective recruitment of motor proteins to autophagic compartments contributes to autophagic failure in aging

Inability to preserve proteostasis with age contributes to the gradual loss of function that characterizes old organisms. Defective autophagy, a component of the proteostasis network for delivery and degradation of intracellular materials in lysosomes, has been described in multiple old organisms, w...

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Detalles Bibliográficos
Autores principales: Bejarano, Eloy, Murray, John W., Wang, Xintao, Pampliega, Olatz, Yin, David, Patel, Bindi, Yuste, Andrea, Wolkoff, Allan W., Cuervo, Ana Maria
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052466/
https://www.ncbi.nlm.nih.gov/pubmed/29845728
http://dx.doi.org/10.1111/acel.12777

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052466/
https://www.ncbi.nlm.nih.gov/pubmed/29845728
http://dx.doi.org/10.1111/acel.12777

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