Restoring mitochondrial DNA copy number preserves mitochondrial function and delays vascular aging in mice

Aging is the largest risk factor for cardiovascular disease, yet the molecular mechanisms underlying vascular aging remain unclear. Mitochondrial DNA (mtDNA) damage is linked to aging, but whether mtDNA damage or mitochondrial dysfunction is present and directly promotes vascular aging is unknown. F...

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Detalles Bibliográficos
Autores principales: Foote, Kirsty, Reinhold, Johannes, Yu, Emma P. K., Figg, Nichola L., Finigan, Alison, Murphy, Michael P., Bennett, Martin R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052475/
https://www.ncbi.nlm.nih.gov/pubmed/29745022
http://dx.doi.org/10.1111/acel.12773

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052475/
https://www.ncbi.nlm.nih.gov/pubmed/29745022
http://dx.doi.org/10.1111/acel.12773

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