CTC1‐STN1 coordinates G‐ and C‐strand synthesis to regulate telomere length

Coats plus (CP) is a rare autosomal recessive disorder caused by mutations in CTC1, a component of the CST (CTC1, STN1, and TEN1) complex important for telomere length maintenance. The molecular basis of how CP mutations impact upon telomere length remains unclear. The CP CTC1(L1142H) mutation has b...

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Detalles Bibliográficos
Autores principales: Gu, Peili, Jia, Shuting, Takasugi, Taylor, Smith, Eric, Nandakumar, Jayakrishnan, Hendrickson, Eric, Chang, Sandy
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479/
https://www.ncbi.nlm.nih.gov/pubmed/29774655
http://dx.doi.org/10.1111/acel.12783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052479/
https://www.ncbi.nlm.nih.gov/pubmed/29774655
http://dx.doi.org/10.1111/acel.12783

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