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Differential aging‐related changes in neurophysiology and gene expression in IB4‐positive and IB4‐negative nociceptive neurons

Despite pain prevalence altering with age, the effects of aging on the properties of nociceptors are not well understood. Nociceptors, whose somas are located in dorsal root ganglia, are frequently divided into two groups based on their ability to bind isolectin B4 (IB4). Here, using cultured neuron...

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Detalles Bibliográficos
Autores principales: Mis, Malgorzata A., Rogers, Mark F., Jeffries, Aaron R., Wilbrey, Anna L., Chen, Lubin, Yang, Yang, Dib‐Hajj, Sulayman, Waxman, Stephen G., Stevens, Edward B., Randall, Andrew D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC6052481/
https://www.ncbi.nlm.nih.gov/pubmed/29943484
http://dx.doi.org/10.1111/acel.12795